Session 4: Getting too sweet during pregnancy: Gestational diabetes
08:30–10:30
Chairs: Ole Christiansen (Denmark) & Udo Jeschke (Germany)
08:30–08:55
Evidence of tissue specific alterations in inflammatory profiles in Gestational Diabetes Mellitus
Cathal M. McCarthy, University College Cork (Ireland)08:55–09:20
Interaction between Glucose, Extracellular Vesicles and Placenta Function in Gestational Diabetes
Karen Forbes, Leeds University (UK)09:20–09:45
Human Milk Oligosaccharides: Emerging Roles in Gestational Diabetes
Evelyn Jantscher-Krenn, Graz University (Austria)09:45–09:55
The immune and metabolic phenotype is changed in fetal livers upon systemic sFLT1 expression in preeclamptic mice which is linked to adverse offspring metabolic responses.
Alina Riedel, University Hospital Essen (Germany)09:55–10:05
Temporal dynamics of immune landscape throughout the menstrual cycle
Lingtao Yang, Shenzhen Zhongshan Urology Hospital (China)10:05–10:15
Effect of RODI OVA™ supplementation on FSH levels and FSH/LH ratio in perimenopausal women with difficulty conceiving.
Barbara Geladakis, RODI Fertility (Greece)10:15–10:25
Dyslipidemia is associated with gal-1 deficient pregnancies
Ulrike Bruening, MDC Berlin (Germany)
10:30–11:00 Coffee Break
Session 5: Viral infections as threat to pregnancy
11:00–13:00
Chair: Theodora Karamitsoglou (Greece) & Evelyin Huhn (Germany)
11:00–11:25
Offspring born to influenza A virus infected pregnant mice show increased vulnerability to viral and bacterial infections in early life
Stephanie Stanelle-Bertram, Leibniz Institute of Virology (Germany)11:25–11:50
Impact of viral infections during pregnancy on trophoblast function
Gil Mor, Wayne State University (USA)11:50–12:15
Cytokine signalling and anti-viral immunity in early life
James Harker, Imperial College (UK)12:15–12:25
SARS-CoV-2 infection, inflammation and obstetric outcomes in a prospective NYC pregnancy cohort.
Frederieke Gigase, Icahn School of Medicine (USA)12:25–12:35
Differential cellular immune response in pregnant and non-pregnant women upon vaccination against SARS-CoV-2 infection
Christopher Urbschat, UKE (Germany)12:35–12:45
Mirrors of the placenta: altered profile of placenta-derived extracellular vesicles upon SARS-CoV-2 infection
Isabel Graf, UKE (Germany)12:45–12:55
Decidual Stromal Cell Ferroptosis Associated with Abnormal Iron Metabolism Is Implicated in the Pathogenesis of Recurrent Pregnancy Loss
Songcun Wang, Fudan University (China)
13:00–14:00 Lunch Break & ISIR Meeting of the General Assembly
Session 6: What vaccinations are recommended during pregnancy?
14:00–16:00
Chair: Marigoula Varla-Leftheriotis (Greece) & Bettina Hollwitz (Germany)
14:00–14:25
Unleashing the Power of Vaccines: Safeguarding Maternal and Fetal Health through Immunization during Pregnancy
Marylyn Addo, UKE (Germany)14:25–14:50
Non-specific effects of vaccines – relevant to pregnant women?
Christine Stabell Benn, Danish Institute for Advanced Study (Denmark)14:50–15:15
Developing mouse models to test vaccines or therapeutics for viral infections in pregnancy
Daniela Verthelyi, U.S. Food and Drug Administration (USA)15:15–15:25
Vertical transfer of maternal pathogen-specific antibodies in successive pregnancies and infection risk in infancy
Ioannis Belios, UKE (Germany)15:25–15:35
Spatial composition of decidual immune cells in oocyte donation pregnancies in relation to fetal-maternal HLA incompatibility
Xuezi Tian, Leiden University Medical Center (The Netherlands)15:35–15:45
Strong anti-fetal HLA antibodies are associated with recurrent pregnancy loss with a diagnosis of chronic histiocytic intervillositis
Ole Christiansen, Aalborg University Hospital (Denmark)15:45–15:55
The Effectiveness of IVIg in Improving Pregnancy Outcome among Patients with Recurrent Pregnancy Loss from Autoimmune Causes
Christine Manalili-Trinidad, University of the Philippines-Philippine General Hospital (Philippines)
16:00–16:30 Coffee Break
Session 7: Early determinants of child health
16:30–18:30
Chairs: Thomas Kroneis (Austria) & Michael Eikmans (The Netherlands)
- 16:30–16:55
Microchimerism and Reproduction: Both Self and Not Self
J. Lee Nelson, Fred Hutchinson Cancer Research Center (USA)16:55–17:20
We All Are Multitudes: Microchimerism, Evolution and Health
Thomas Kroneis, University Graz (Austria)17:20–17:45
Placental dysfunction and increased fetal cell transfer: providing long-lasting cardiovascular messages to the mother?
Annetine Staff, Oslo University (Norway)17:45–17:55
The immunological intrigue of microchimerism: tracing fetal and maternal cells throughout the body
Romy Buwalda-Smit, University of Groningen (Netherlands)17:55–18:05
Placenta-derived extracellular vesicles as liquid biopsy for placental transfer
Dennis Yüzen, UKE (Germany)18:05–18:15
A microfluidic-supported model for the study of placental transfer mechanisms
Wenting Cao, Jena University Hospital (Germany)18:15–18:25
Pregnancy-induced memory CD4+ regulatory T cells: identification of specific immune memory markers using Infinity Flow
Kristin Thiele, UKE (Germany)
